PRMT7 Inhibitor SGC8158 Enhances Doxorubicin-Induced DNA Damage and Its Cytotoxicity

Protein arginine methyltransferase 7 (PRMT7) regulates various cellular responses, including gene expression, cell migration, stress responses, and stemness. In this study, we investigated the biological role of PRMT7 in cell cycle progression and DNA damage response (DDR) by inhibiting PRMT7 activi...

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Detalles Bibliográficos
Autores principales: Jeong, Ahyeon, Cho, Yena, Cho, Minkyeong, Bae, Gyu-Un, Song, Dae-Geun, Kim, Su-Nam, Kim, Yong Kee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604017/
https://www.ncbi.nlm.nih.gov/pubmed/36293180
http://dx.doi.org/10.3390/ijms232012323

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604017/
https://www.ncbi.nlm.nih.gov/pubmed/36293180
http://dx.doi.org/10.3390/ijms232012323

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