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Insulin Diminishes Superoxide Increase in Cytosol and Mitochondria of Cultured Cortical Neurons Treated with Toxic Glutamate

Glutamate excitotoxicity is involved in the pathogenesis of many disorders, including stroke, traumatic brain injury, and Alzheimer’s disease, for which central insulin resistance is a comorbid condition. Neurotoxicity of glutamate (Glu) is primarily associated with hyperactivation of the ionotropic...

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Detalles Bibliográficos
Autores principales: Pinelis, Vsevolod, Krasilnikova, Irina, Bakaeva, Zanda, Surin, Alexander, Boyarkin, Dmitrii, Fisenko, Andrei, Krasilnikova, Olga, Pomytkin, Igor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604026/
https://www.ncbi.nlm.nih.gov/pubmed/36293449
http://dx.doi.org/10.3390/ijms232012593