Identification of Candidate mRNA Isoforms for Prostate Cancer-Risk SNPs Utilizing Iso-eQTL and sQTL Methods

Single nucleotide polymorphisms (SNPs) impacting the alternative splicing (AS) process (sQTLs) or isoform expression (iso-eQTL) are implicated as important cancer regulatory elements. To find the sQTL and iso-eQTL, we retrieved prostate cancer (PrCa) tissue RNA-seq and genotype data originating from...

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Detalles Bibliográficos
Autores principales: Moradi, Afshin, Sharma, Harsh, Sharma, Ravi Datta, Fernando, Achala, Barrero, Roberto A., Batra, Jyotsna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604153/
https://www.ncbi.nlm.nih.gov/pubmed/36293264
http://dx.doi.org/10.3390/ijms232012406

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604153/
https://www.ncbi.nlm.nih.gov/pubmed/36293264
http://dx.doi.org/10.3390/ijms232012406

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