Anion-Exchange Chromatography at the Service of Gene Therapy: Baseline Separation of Full/Empty Adeno-Associated Virus Capsids by Screening of Conditions and Step Gradient Elution Mode

Gene therapy is opening unprecedented opportunities for novel therapeutic approaches. Based on the concept of rescuing function mutations by co-expressing the correct gene to allow biological functions to be restored, it requires the use of viral vectors to ensure the proper delivery of therapeutic...

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Detalles Bibliográficos
Autores principales: Aebischer, Megane K., Gizardin-Fredon, Hugo, Lardeux, Honorine, Kochardt, Dominik, Elger, Carsten, Haindl, Markus, Ruppert, Raphael, Guillarme, Davy, D’Atri, Valentina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604245/
https://www.ncbi.nlm.nih.gov/pubmed/36293189
http://dx.doi.org/10.3390/ijms232012332

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604245/
https://www.ncbi.nlm.nih.gov/pubmed/36293189
http://dx.doi.org/10.3390/ijms232012332

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