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Role of Glycolysis and Fatty Acid Synthesis in the Activation and T Cell-Modulating Potential of Dendritic Cells Stimulated with a TLR5-Ligand Allergen Fusion Protein

Trained immune responses, based on metabolic and epigenetic changes in innate immune cells, are de facto innate immune memory and, therefore, are of great interest in vaccine development. In previous studies, the recombinant fusion protein rFlaA:Betv1, combining the adjuvant and toll-like receptor (...

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Detalles Bibliográficos
Autores principales: Goretzki, Alexandra, Lin, Yen-Ju, Zimmermann, Jennifer, Rainer, Hannah, Junker, Ann-Christine, Wolfheimer, Sonja, Vieths, Stefan, Scheurer, Stephan, Schülke, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604253/
https://www.ncbi.nlm.nih.gov/pubmed/36293550
http://dx.doi.org/10.3390/ijms232012695