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Heparanase Increases Podocyte Survival and Autophagic Flux after Adriamycin-Induced Injury
The kidney glomerular filtration barrier (GFB) is enriched with heparan sulfate (HS) proteoglycans, which contribute to its permselectivity. The endoglycosidase heparanase cleaves HS and hence appears to be involved in the pathogenesis of kidney injury and glomerulonephritis. We have recently report...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604275/ https://www.ncbi.nlm.nih.gov/pubmed/36293542 http://dx.doi.org/10.3390/ijms232012691 |