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Heparanase Increases Podocyte Survival and Autophagic Flux after Adriamycin-Induced Injury

The kidney glomerular filtration barrier (GFB) is enriched with heparan sulfate (HS) proteoglycans, which contribute to its permselectivity. The endoglycosidase heparanase cleaves HS and hence appears to be involved in the pathogenesis of kidney injury and glomerulonephritis. We have recently report...

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Detalles Bibliográficos
Autores principales: Abu-Tayeh Suleiman, Hanan, Said, Shereen, Ali Saleh, Haya, Gamliel-Lazarovich, Aviva, Haddad, Eyas, Minkov, Irina, Zohar, Yaniv, Ilan, Neta, Vlodavsky, Israel, Abassi, Zaid, Assady, Suheir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604275/
https://www.ncbi.nlm.nih.gov/pubmed/36293542
http://dx.doi.org/10.3390/ijms232012691