Rat Group IIA Secreted Phospholipase A(2) Binds to Cytochrome c Oxidase and Inhibits Its Activity: A Possible Episode in the Development of Alzheimer’s Disease

Alzheimer’s disease (AD), a progressive form of dementia, is characterized by the increased expression of secreted phospholipase A(2) group IIA (GIIA) in the affected tissue and the dysfunction of neuronal mitochondria, similar to that induced by an orthologous GIIA from snake venom, β-neurotoxic am...

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Detalles Bibliográficos
Autores principales: Ivanušec, Adrijan, Šribar, Jernej, Leonardi, Adrijana, Zorović, Maja, Živin, Marko, Križaj, Igor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604285/
https://www.ncbi.nlm.nih.gov/pubmed/36293221
http://dx.doi.org/10.3390/ijms232012368

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604285/
https://www.ncbi.nlm.nih.gov/pubmed/36293221
http://dx.doi.org/10.3390/ijms232012368

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