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Rat Group IIA Secreted Phospholipase A(2) Binds to Cytochrome c Oxidase and Inhibits Its Activity: A Possible Episode in the Development of Alzheimer’s Disease
Alzheimer’s disease (AD), a progressive form of dementia, is characterized by the increased expression of secreted phospholipase A(2) group IIA (GIIA) in the affected tissue and the dysfunction of neuronal mitochondria, similar to that induced by an orthologous GIIA from snake venom, β-neurotoxic am...
Autores principales: | Ivanušec, Adrijan, Šribar, Jernej, Leonardi, Adrijana, Zorović, Maja, Živin, Marko, Križaj, Igor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604285/ https://www.ncbi.nlm.nih.gov/pubmed/36293221 http://dx.doi.org/10.3390/ijms232012368 |
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