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Repurposing SGLT-2 Inhibitors to Target Aging: Available Evidence and Molecular Mechanisms
Caloric restriction promotes longevity in multiple animal models. Compounds modulating nutrient-sensing pathways have been suggested to reproduce part of the beneficial effect of caloric restriction on aging. However, none of the commonly studied caloric restriction mimetics actually produce a decre...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604287/ https://www.ncbi.nlm.nih.gov/pubmed/36293181 http://dx.doi.org/10.3390/ijms232012325 |