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Repurposing SGLT-2 Inhibitors to Target Aging: Available Evidence and Molecular Mechanisms

Caloric restriction promotes longevity in multiple animal models. Compounds modulating nutrient-sensing pathways have been suggested to reproduce part of the beneficial effect of caloric restriction on aging. However, none of the commonly studied caloric restriction mimetics actually produce a decre...

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Detalles Bibliográficos
Autores principales:	La Grotta, Rosalba, Frigé, Chiara, Matacchione, Giulia, Olivieri, Fabiola, de Candia, Paola, Ceriello, Antonio, Prattichizzo, Francesco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604287/ https://www.ncbi.nlm.nih.gov/pubmed/36293181 http://dx.doi.org/10.3390/ijms232012325

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