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PGC-1α and MEF2 Regulate the Transcription of the Carnitine Transporter OCTN2 Gene in C2C12 Cells and in Mouse Skeletal Muscle

OCTN2 (SLC22A5) is a carnitine transporter whose main function is the active transport of carnitine into cells. In skeletal muscle and other organs, the regulation of the SLC22A5 gene transcription has been shown to depend on the nuclear transcription factor PPAR-α. Due to the observation that the m...

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Detalles Bibliográficos
Autores principales: Novakova, Katerina, Török, Michael, Panajatovic, Miljenko, Bouitbir, Jamal, Duong, François H. T., Handschin, Christoph, Krähenbühl, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604316/
https://www.ncbi.nlm.nih.gov/pubmed/36293168
http://dx.doi.org/10.3390/ijms232012304