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The Citrus Flavonoid Nobiletin Downregulates Angiopoietin-like Protein 3 (ANGPTL3) Expression and Exhibits Lipid-Modulating Effects in Hepatic Cells and Adult Zebrafish Models

Nobiletin, a dietary citrus flavonoid, exerts biological activities against hyperlipidemia, obesity, and atherosclerotic cardiovascular diseases (ASCVDs). The aim of this study was to explore the lipid-lowering effects of nobiletin and the underlying molecular mechanisms in vitro in hepatic cells an...

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Detalles Bibliográficos
Autores principales: Lin, Ching-Yen, Chen, Pei-Yi, Hsu, Hao-Jen, Gao, Wan-Yun, Wu, Ming-Jiuan, Yen, Jui-Hung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604320/
https://www.ncbi.nlm.nih.gov/pubmed/36293338
http://dx.doi.org/10.3390/ijms232012485