The Third Extracellular Loop of Mammalian Odorant Receptors Is Involved in Ligand Binding

Mammals recognize chemicals in the air via G protein-coupled odorant receptors (ORs). In addition to their orthosteric binding site, other segments of these receptors modulate ligand recognition. Focusing on human hOR1A1, which is considered prototypical of class II ORs, we used a combination of mol...

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Detalles Bibliográficos
Autores principales: Shim, Tammy, Pacalon, Jody, Kim, Won-Cheol, Cong, Xiaojing, Topin, Jérémie, Golebiowski, Jérôme, Moon, Cheil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604345/
https://www.ncbi.nlm.nih.gov/pubmed/36293357
http://dx.doi.org/10.3390/ijms232012501

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604345/
https://www.ncbi.nlm.nih.gov/pubmed/36293357
http://dx.doi.org/10.3390/ijms232012501

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