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The Third Extracellular Loop of Mammalian Odorant Receptors Is Involved in Ligand Binding
Mammals recognize chemicals in the air via G protein-coupled odorant receptors (ORs). In addition to their orthosteric binding site, other segments of these receptors modulate ligand recognition. Focusing on human hOR1A1, which is considered prototypical of class II ORs, we used a combination of mol...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604345/ https://www.ncbi.nlm.nih.gov/pubmed/36293357 http://dx.doi.org/10.3390/ijms232012501 |