Bergamottin and PAP-1 Induced ACE2 Degradation to Alleviate Infection of SARS-CoV-2

Angiotensin-converting enzyme 2 (ACE2), a functional receptor for SARS-CoV, now appears likely to mediate 2019-nCoV entry into human cells. However, inhibitors such as PAP-1 and bergamottin have been discovered; both of them can preferentially bind to ACE2, prevent RBD Spike S protein from binding t...

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Detalles Bibliográficos
Autores principales: Li, Mengjia, Zhang, Yongzheng, Zeb, Amir, Wu, Yang, Cheng, Lufeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604380/
https://www.ncbi.nlm.nih.gov/pubmed/36293419
http://dx.doi.org/10.3390/ijms232012565

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604380/
https://www.ncbi.nlm.nih.gov/pubmed/36293419
http://dx.doi.org/10.3390/ijms232012565

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