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Drug Resistance (Dapsone, Rifampicin, Ofloxacin) and Resistance-Related Gene Mutation Features in Leprosy Patients: A Systematic Review and Meta-Analysis

Dapsone (DDS), Rifampicin (RIF) and Ofloxacin (OFL) are drugs recommended by the World Health Organization (WHO) for the treatment of leprosy. In the context of leprosy, resistance to these drugs occurs mainly due to mutations in the target genes (Folp1, RpoB and GyrA). It is important to monitor an...

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Detalles Bibliográficos
Autores principales: Li, Xiang, Li, Guoli, Yang, Jing, Jin, Guangjie, Shao, Yuting, Li, Yunhui, Wei, Pingmin, Zhang, Lianhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604410/
https://www.ncbi.nlm.nih.gov/pubmed/36293307
http://dx.doi.org/10.3390/ijms232012443