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Clostridioides difficile Flagellin Activates the Intracellular NLRC4 Inflammasome

Clostridioides difficile (C. difficile), is a major cause of nosocomial diarrhea and colitis. C. difficile flagellin FliC contributes toxins to gut inflammation by interacting with the immune Toll-like receptor 5 (TLR5) to activate nuclear factor-kappa B (NF-kB) and mitogen-activated protein kinase...

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Detalles Bibliográficos
Autores principales: Chebly, Hiba, Marvaud, Jean-Christophe, Safa, Layale, Elkak, Assem Khalil, Kobeissy, Philippe Hussein, Kansau, Imad, Larrazet, Cécile
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604438/
https://www.ncbi.nlm.nih.gov/pubmed/36293218
http://dx.doi.org/10.3390/ijms232012366