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Clostridioides difficile Flagellin Activates the Intracellular NLRC4 Inflammasome
Clostridioides difficile (C. difficile), is a major cause of nosocomial diarrhea and colitis. C. difficile flagellin FliC contributes toxins to gut inflammation by interacting with the immune Toll-like receptor 5 (TLR5) to activate nuclear factor-kappa B (NF-kB) and mitogen-activated protein kinase...
Autores principales: | Chebly, Hiba, Marvaud, Jean-Christophe, Safa, Layale, Elkak, Assem Khalil, Kobeissy, Philippe Hussein, Kansau, Imad, Larrazet, Cécile |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604438/ https://www.ncbi.nlm.nih.gov/pubmed/36293218 http://dx.doi.org/10.3390/ijms232012366 |
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