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Association between Changes in the Patterns of Antinuclear Autoantibodies during Immune Checkpoint Inhibition Therapy and the Development of Severe Immune Related Adverse Events

Immune-related adverse events (irAEs) are unpredictable autoimmune-like toxicities induced by immune checkpoint inhibitors (ICI). irAEs are a consequence of a breakdown in self-tolerance. ICIs can induce autoantibody formation, and the presence of antinuclear autoantibodies (ANAs) has been reported...

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Detalles Bibliográficos
Autores principales: Alserawan, Leticia, Anguera, Geòrgia, Zamora Atenza, Carlos, Serra López, Jorgina, Martínez-Martínez, Laura, Riudavets Melià, Mariona, Sullivan, Ivana, Barba Joaquin, Andrés, Majem Tarruella, Margarita, Vidal, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604501/
https://www.ncbi.nlm.nih.gov/pubmed/36293498
http://dx.doi.org/10.3390/ijms232012641