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Non-Reproducibility of Oral Rotenone as a Model for Parkinson’s Disease in Mice

Oral rotenone has been proposed as a model for Parkinson’s disease (PD) in mice. To establish the model in our lab and study complex behavior we followed a published treatment regimen. C57BL/6 mice received 30 mg/kg body weight of rotenone once daily via oral administration for 4 and 8 weeks. Motor...

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Detalles Bibliográficos
Autores principales: Niederberger, Ellen, Wilken-Schmitz, Annett, Manderscheid, Christine, Schreiber, Yannick, Gurke, Robert, Tegeder, Irmgard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604506/
https://www.ncbi.nlm.nih.gov/pubmed/36293513
http://dx.doi.org/10.3390/ijms232012658