Reversible Platelet Integrin αIIbβ3 Activation and Thrombus Instability

Integrin αIIbβ3 activation is essential for platelet aggregation and, accordingly, for hemostasis and arterial thrombosis. The αIIbβ3 integrin is highly expressed on platelets and requires an activation step for binding to fibrinogen, fibrin or von Willebrand factor (VWF). A current model assumes th...

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Detalles Bibliográficos
Autores principales: Zou, Jinmi, Swieringa, Frauke, de Laat, Bas, de Groot, Philip G., Roest, Mark, Heemskerk, Johan W. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604507/
https://www.ncbi.nlm.nih.gov/pubmed/36293367
http://dx.doi.org/10.3390/ijms232012512

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604507/
https://www.ncbi.nlm.nih.gov/pubmed/36293367
http://dx.doi.org/10.3390/ijms232012512

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