De novo selected hACE2 mimics that integrate hotspot peptides with aptameric scaffolds for binding tolerance of SARS-CoV-2 variants

The frequent occurrence of viral variants is a critical problem in developing antiviral prophylaxis and therapy; along with stronger recognition of host cell receptors, the variants evade the immune system–based vaccines and neutralizing agents more easily. In this work, we focus on enhanced recepto...

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Detalles Bibliográficos
Autores principales: Lee, Minjong, Kang, Byunghwa, Lee, Juhwa, Lee, Jisun, Jung, Sang Taek, Son, Chang Yun, Oh, Seung Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604513/
https://www.ncbi.nlm.nih.gov/pubmed/36288301
http://dx.doi.org/10.1126/sciadv.abq6207

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604513/
https://www.ncbi.nlm.nih.gov/pubmed/36288301
http://dx.doi.org/10.1126/sciadv.abq6207

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