H4K5 Butyrylation Coexist with Acetylation during Human Spermiogenesis and Are Retained in the Mature Sperm Chromatin

Male germ cells experience a drastic chromatin remodeling through the nucleo-histone to nucleo-protamine (NH-NP) transition necessary for proper sperm functionality. Post-translational modifications (PTMs) of H4 Lys5, such as acetylation (H4K5ac), play a crucial role in epigenetic control of nucleos...

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Detalles Bibliográficos
Autores principales: de la Iglesia, Alberto, Jauregi, Paula, Jodar, Meritxell, Barrachina, Ferran, Ded, Lukas, Mallofré, Carme, Rodríguez-Carunchio, Leonardo, Corral, Juan Manuel, Ballescà, Josep Lluís, Komrskova, Katerina, Castillo, Judit, Oliva, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604518/
https://www.ncbi.nlm.nih.gov/pubmed/36293256
http://dx.doi.org/10.3390/ijms232012398

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604518/
https://www.ncbi.nlm.nih.gov/pubmed/36293256
http://dx.doi.org/10.3390/ijms232012398

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