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LC3-associated endocytosis and the functions of Rubicon and ATG16L1

LC3-associated endocytosis (LANDO) is a noncanonical function of the autophagy machinery, in which LC3 (microtubule-associated protein light chain) is conjugated to rab5-positive endosomes, using a portion of the canonical autophagy pathway. LANDO was initially discovered in a murine model of Alzhei...

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Detalles Bibliográficos
Autores principales: Magné, Joëlle, Green, Douglas R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604520/
https://www.ncbi.nlm.nih.gov/pubmed/36288306
http://dx.doi.org/10.1126/sciadv.abo5600