Control of infection by LC3-associated phagocytosis, CASM, and detection of raised vacuolar pH by the V-ATPase-ATG16L1 axis

The delivery of pathogens to lysosomes for degradation provides an important defense against infection. Degradation is enhanced when LC3 is conjugated to endosomes and phagosomes containing pathogens to facilitate fusion with lysosomes. In phagocytic cells, TLR signaling and Rubicon activate LC3-ass...

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Detalles Bibliográficos
Autores principales: Wang, Yingxue, Ramos, Maria, Jefferson, Matthew, Zhang, Weijiao, Beraza, Naiara, Carding, Simon, Powell, Penny P., Stewart, James P., Mayer, Ulrike, Wileman, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Biomedicine and Life Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604538/
https://www.ncbi.nlm.nih.gov/pubmed/36288298
http://dx.doi.org/10.1126/sciadv.abn3298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604538/
https://www.ncbi.nlm.nih.gov/pubmed/36288298
http://dx.doi.org/10.1126/sciadv.abn3298

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