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cd(1) Mutation in Drosophila Affects Phenoxazinone Synthase Catalytic Site and Impairs Long-Term Memory

Being involved in development of Huntington’s, Parkinson’s and Alzheimer’s diseases, kynurenine pathway (KP) of tryptophan metabolism plays a significant role in modulation of neuropathology. Accumulation of a prooxidant 3-hydroxykynurenine (3-HOK) leads to oxidative stress and neuronal cell apoptos...

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Detalles Bibliográficos
Autores principales: Zhuravlev, Aleksandr V., Ivanova, Polina N., Makaveeva, Ksenia A., Zakharov, Gennadii A., Nikitina, Ekaterina A., Savvateeva-Popova, Elena V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604555/
https://www.ncbi.nlm.nih.gov/pubmed/36293213
http://dx.doi.org/10.3390/ijms232012356