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Regulation of α-synuclein homeostasis and inflammasome activation by microglial autophagy

Autophagy clears protein aggregates, damaged cellular organelles, and pathogens through the lysosome. Although autophagy is highly conserved across all cell types, its activity in each cell is specifically adapted to carry out distinct physiological functions. The role of autophagy in neurons has be...

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Detalles Bibliográficos
Autores principales: Choi, Insup, Heaton, George R., Lee, You-Kyung, Yue, Zhenyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604594/
https://www.ncbi.nlm.nih.gov/pubmed/36288297
http://dx.doi.org/10.1126/sciadv.abn1298