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Regulation of α-synuclein homeostasis and inflammasome activation by microglial autophagy
Autophagy clears protein aggregates, damaged cellular organelles, and pathogens through the lysosome. Although autophagy is highly conserved across all cell types, its activity in each cell is specifically adapted to carry out distinct physiological functions. The role of autophagy in neurons has be...
Autores principales: | Choi, Insup, Heaton, George R., Lee, You-Kyung, Yue, Zhenyu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604594/ https://www.ncbi.nlm.nih.gov/pubmed/36288297 http://dx.doi.org/10.1126/sciadv.abn1298 |
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