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Impact of aging and oxidative stress on specific components of excitation contraction coupling in regulating force generation

Muscle weakness associated with sarcopenia is a major contributor to reduced health span and quality of life in the elderly. However, the underlying mechanisms of muscle weakness in aging are not fully defined. We investigated the effect of oxidative stress and aging on specific molecular mechanisms...

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Detalles Bibliográficos
Autores principales: Xu, Hongyang, Ahn, Bumsoo, Van Remmen, Holly
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604602/
https://www.ncbi.nlm.nih.gov/pubmed/36288318
http://dx.doi.org/10.1126/sciadv.add7377