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Unusual Tetrahydropyridoindole-Containing Tetrapeptides with Human Nicotinic Acetylcholine Receptors Targeting Activity Discovered from Antarctica-Derived Psychrophilic Pseudogymnoascus sp. HDN17-933

Chemical investigation of the psychrophilic fungus Pseudogymnoascus sp. HDN17-933 derived from Antarctica led to the discovery of six new tetrapeptides psegymamides A–F (1–6), whose planar structures were elucidated by extensive NMR and MS spectrometric analyses. Structurally, psegymamides D–F (4–6)...

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Detalles Bibliográficos
Autores principales: Hou, Xuewen, Li, Changlong, Zhang, Runfang, Li, Yinping, Li, Huadong, Zhang, Yundong, Tae, Han-Shen, Yu, Rilei, Che, Qian, Zhu, Tianjiao, Li, Dehai, Zhang, Guojian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604729/
https://www.ncbi.nlm.nih.gov/pubmed/36286417
http://dx.doi.org/10.3390/md20100593