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Caspase-1 and Cathepsin B Inhibitors from Marine Invertebrates, Aiming at a Reduction in Neuroinflammation

Neuroinflammation is a condition associated with several types of dementia, such as Alzheimer’s disease (AD), mainly caused by an inflammatory response to amyloid peptides that induce microglial activation, with subsequent cytokine release. Neuronal caspase-1 from inflammasome and cathepsin B are ke...

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Detalles Bibliográficos
Autores principales: Moreno, Rafaela Indalecio, Zambelli, Vanessa O., Picolo, Gisele, Cury, Yara, Morandini, André C., Marques, Antonio Carlos, Sciani, Juliana Mozer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604745/
https://www.ncbi.nlm.nih.gov/pubmed/36286438
http://dx.doi.org/10.3390/md20100614