Cargando…
Global genome decompaction leads to stochastic activation of gene expression as a first step toward fate commitment in human hematopoietic cells
When human cord blood–derived CD34+ cells are induced to differentiate, they undergo rapid and dynamic morphological and molecular transformations that are critical for fate commitment. In particular, the cells pass through a transitory phase known as “multilineage-primed” state. These cells are cha...
| Autores principales: | , , , , , , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2022
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604949/ https://www.ncbi.nlm.nih.gov/pubmed/36288293 http://dx.doi.org/10.1371/journal.pbio.3001849 |