An integrated multi-omics analysis of topoisomerase family in pan-cancer: Friend or foe?

BACKGROUND: Topoisomerases are nuclear enzymes that get to the bottom of topological troubles related with DNA all through a range of genetic procedures. More and more studies have shown that topoisomerase-mediated DNA cleavage plays crucial roles in tumor cell death and carcinogenesis. There is how...

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Detalles Bibliográficos
Autores principales: Zhou, Xin, Yao, Guixiang, Zhang, Jin, Bian, Jiasheng, Li, Guanghao, Xu, Jianfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604985/
https://www.ncbi.nlm.nih.gov/pubmed/36288358
http://dx.doi.org/10.1371/journal.pone.0274546

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9604985/
https://www.ncbi.nlm.nih.gov/pubmed/36288358
http://dx.doi.org/10.1371/journal.pone.0274546

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