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A Clot Waveform Analysis of Thrombin Time Using a Small Amount of Thrombin Is Useful for Evaluating the Clotting Activity of Plasma Independent of the Presence of Emicizumab

Objective: Although emicizumab is a bispecific, monoclonal antibody that has led to a significant improvement of treatment for hemophilia A patients with inhibitors, the routine monitoring of patients treated with emicizumab is difficult. Thrombin time (TT) reflects thrombin burst, which mainly depe...

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Detalles Bibliográficos
Autores principales: Wada, Hideo, Shiraki, Katsuya, Matsumoto, Takeshi, Suzuki, Kei, Yamashita, Yoshiki, Tawara, Isao, Shimpo, Hideto, Shimaoka, Motomu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605059/
https://www.ncbi.nlm.nih.gov/pubmed/36294464
http://dx.doi.org/10.3390/jcm11206142