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Calcineurin Inhibitors Synergize with Manogepix to Kill Diverse Human Fungal Pathogens

Invasive fungal infections have mortality rates of 30–90%, depending on patient co-morbidities and the causative pathogen. The frequent emergence of drug resistance reduces the efficacy of currently approved treatment options, highlighting an urgent need for antifungals with new modes of action. Add...

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Detalles Bibliográficos
Autores principales: Liston, Sean D., Whitesell, Luke, Kapoor, Mili, Shaw, Karen J., Cowen, Leah E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605145/
https://www.ncbi.nlm.nih.gov/pubmed/36294667
http://dx.doi.org/10.3390/jof8101102