Total Synthesis and Biological Evaluation of Modified Ilamycin Derivatives

Ilamycins/rufomycins are marine cycloheptapeptides containing unusual amino acids. Produced by Streptomyces sp., these compounds show potent activity against a range of mycobacteria, including multidrug-resistant strains of Mycobacterium tuberculosis. The cyclic peptides target the AAA+ protein ClpC...

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Detalles Bibliográficos
Autores principales: Greve, Jennifer, Mogk, Axel, Kazmaier, Uli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605216/
https://www.ncbi.nlm.nih.gov/pubmed/36286456
http://dx.doi.org/10.3390/md20100632

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605216/
https://www.ncbi.nlm.nih.gov/pubmed/36286456
http://dx.doi.org/10.3390/md20100632

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