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TLR2 axis on peripheral blood mononuclear cells regulates inflammatory responses to non-infectious immature dengue virus particles

Severe dengue virus (DENV) infection is characterized by exacerbated inflammatory responses that lead to endothelial dysfunction and plasma leakage. We have recently demonstrated that Toll-like receptor 2 (TLR2) on blood monocytes senses DENV infection leading to endothelial activation. Here, we rep...

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Detalles Bibliográficos
Autores principales: Aguilar Briseño, José Alberto, Ramos Pereira, Lennon, van der Laan, Marleen, Pauzuolis, Mindaugas, ter Ellen, Bram M., Upasani, Vinit, Moser, Jill, de Souza Ferreira, Luís Carlos, Smit, Jolanda M., Rodenhuis-Zybert, Izabela A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605289/
https://www.ncbi.nlm.nih.gov/pubmed/36240261
http://dx.doi.org/10.1371/journal.ppat.1010499