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TLR2 axis on peripheral blood mononuclear cells regulates inflammatory responses to non-infectious immature dengue virus particles
Severe dengue virus (DENV) infection is characterized by exacerbated inflammatory responses that lead to endothelial dysfunction and plasma leakage. We have recently demonstrated that Toll-like receptor 2 (TLR2) on blood monocytes senses DENV infection leading to endothelial activation. Here, we rep...
Autores principales: | Aguilar Briseño, José Alberto, Ramos Pereira, Lennon, van der Laan, Marleen, Pauzuolis, Mindaugas, ter Ellen, Bram M., Upasani, Vinit, Moser, Jill, de Souza Ferreira, Luís Carlos, Smit, Jolanda M., Rodenhuis-Zybert, Izabela A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605289/ https://www.ncbi.nlm.nih.gov/pubmed/36240261 http://dx.doi.org/10.1371/journal.ppat.1010499 |
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