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Daratumumab Interferes with Allogeneic Crossmatch Impacting Immunological Assessment in Solid Organ Transplantation

We report the first case of Daratumumab interference of allogeneic crossmatch tests repeatedly causing aberrant false-positive results, which inadvertently delayed transplant for a waitlisted renal patient with multiple myeloma. Daratumumab is an IgG1κ human monoclonal antibody commonly used to trea...

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Detalles Bibliográficos
Autores principales: Ho, Chak-Sum, Putnam, Kyle R., Peiter, Christine R., Herczyk, Walter F., Gerlach, John A., Lu, Yee, Campagnaro, Erica L., Woodside, Kenneth J., Cusick, Matthew F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605360/
https://www.ncbi.nlm.nih.gov/pubmed/36294380
http://dx.doi.org/10.3390/jcm11206059