Cytotoxic N-Methylpretrichodermamide B Reveals Anticancer Activity and Inhibits P-Glycoprotein in Drug-Resistant Prostate Cancer Cells

N-methylpretrichodermamide B (NB) is a biologically active epidithiodiketopiperazine isolated from several strains of the algae-derived fungus Penicillium sp. Recently, we reported the first data on its activity in human cancer cells lines in vitro. Here, we investigated the activity, selectivity, a...

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Detalles Bibliográficos
Autores principales: Dyshlovoy, Sergey A., Busenbender, Tobias, Hauschild, Jessica, Girich, Elena V., Kriegs, Malte, Hoffer, Konstantin, Graefen, Markus, Yurchenko, Anton N., Bokemeyer, Carsten, von Amsberg, Gunhild
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605374/
https://www.ncbi.nlm.nih.gov/pubmed/36286421
http://dx.doi.org/10.3390/md20100597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605374/
https://www.ncbi.nlm.nih.gov/pubmed/36286421
http://dx.doi.org/10.3390/md20100597

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