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Cytotoxic N-Methylpretrichodermamide B Reveals Anticancer Activity and Inhibits P-Glycoprotein in Drug-Resistant Prostate Cancer Cells
N-methylpretrichodermamide B (NB) is a biologically active epidithiodiketopiperazine isolated from several strains of the algae-derived fungus Penicillium sp. Recently, we reported the first data on its activity in human cancer cells lines in vitro. Here, we investigated the activity, selectivity, a...
Autores principales: | Dyshlovoy, Sergey A., Busenbender, Tobias, Hauschild, Jessica, Girich, Elena V., Kriegs, Malte, Hoffer, Konstantin, Graefen, Markus, Yurchenko, Anton N., Bokemeyer, Carsten, von Amsberg, Gunhild |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605374/ https://www.ncbi.nlm.nih.gov/pubmed/36286421 http://dx.doi.org/10.3390/md20100597 |
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