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Targeting Ca(2+) and Mitochondrial Homeostasis by Antipsychotic Thioridazine in Leukemia Cells

Mitochondria have pivotal roles in cellular physiology including energy metabolism, reactive oxygen species production, Ca(2+) homeostasis, and apoptosis. Altered mitochondrial morphology and function is a common feature of cancer cells and the regulation of mitochondrial homeostasis has been identi...

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Detalles Bibliográficos
Autores principales: Moraes, Vivian W. R., Santos, Vivian M., Suarez, Eloah R., Ferraz, Letícia S., Lopes, Rayssa de Mello, Mognol, Giuliana P., Campeiro, Joana D., Machado-Neto, João A., Nascimento, Fabio D., Hayashi, Mirian A. F., Tersariol, Ivarne L. S., Newmeyer, Donald D., Rodrigues, Tiago
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605445/
https://www.ncbi.nlm.nih.gov/pubmed/36294912
http://dx.doi.org/10.3390/life12101477