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Targeting Ca(2+) and Mitochondrial Homeostasis by Antipsychotic Thioridazine in Leukemia Cells
Mitochondria have pivotal roles in cellular physiology including energy metabolism, reactive oxygen species production, Ca(2+) homeostasis, and apoptosis. Altered mitochondrial morphology and function is a common feature of cancer cells and the regulation of mitochondrial homeostasis has been identi...
Autores principales: | Moraes, Vivian W. R., Santos, Vivian M., Suarez, Eloah R., Ferraz, Letícia S., Lopes, Rayssa de Mello, Mognol, Giuliana P., Campeiro, Joana D., Machado-Neto, João A., Nascimento, Fabio D., Hayashi, Mirian A. F., Tersariol, Ivarne L. S., Newmeyer, Donald D., Rodrigues, Tiago |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605445/ https://www.ncbi.nlm.nih.gov/pubmed/36294912 http://dx.doi.org/10.3390/life12101477 |
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