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The use of predictive models to develop chromatography-based purification processes

Chromatography is the workhorse of biopharmaceutical downstream processing because it can selectively enrich a target product while removing impurities from complex feed streams. This is achieved by exploiting differences in molecular properties, such as size, charge and hydrophobicity (alone or in...

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Detalles Bibliográficos
Autores principales: Bernau, C. R., Knödler, M., Emonts, J., Jäpel, R. C., Buyel, J. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605695/
https://www.ncbi.nlm.nih.gov/pubmed/36312533
http://dx.doi.org/10.3389/fbioe.2022.1009102