A novel method for site-specific chemical SUMOylation: SUMOylation of Hsp90 modulates co-chaperone binding in vitro

SUMO is covalently attached to lysine side chains in target proteins by the action of a cascade of E1, E2, and E3 ligases. Unlike ubiquitin, SUMO does not target proteins for degradation but rather plays a regulatory role in activating target proteins or directing them to multiprotein complexes. Iso...

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Detalles Bibliográficos
Autores principales: Wolmarans, Annemarie, Kwantes, Allison, LaPointe, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: De Gruyter 2019
Materias:
Protein Structure and Function
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605714/
https://www.ncbi.nlm.nih.gov/pubmed/30265648
http://dx.doi.org/10.1515/hsz-2018-0251

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605714/
https://www.ncbi.nlm.nih.gov/pubmed/30265648
http://dx.doi.org/10.1515/hsz-2018-0251

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