Identification of 6ω-cyclohexyl-2-(phenylamino carbonylmethylthio)pyrimidin-4(3H)-ones targeting the ZIKV NS5 RNA dependent RNA polymerase

Zika virus (ZIKV), a mosquito-borne flavivirus, is a global health concern because of its association with severe neurological disorders such as neonatal microcephaly and adult Guillain-Barre syndrome. Although many efforts have been made to combat ZIKV infection, there is currently no approved vacc...

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Detalles Bibliográficos
Autores principales: Zhou, Guang-Feng, Xie, Cong-Qiang, Xue, Jian-Xia, Wang, Jing-Bo, Yang, Yu-Zhuo, Zheng, Chang-Bo, Luo, Rong-Hua, Yang, Ren-Hua, Chen, Wen, Yang, Liu-Meng, Wang, Yue-Ping, Zhang, Hong-Bin, He, Yan-Ping, Zheng, Yong-Tang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605737/
https://www.ncbi.nlm.nih.gov/pubmed/36311427
http://dx.doi.org/10.3389/fchem.2022.1010547

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605737/
https://www.ncbi.nlm.nih.gov/pubmed/36311427
http://dx.doi.org/10.3389/fchem.2022.1010547

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