Antiviral drug design based on structural insights into the N-terminal domain and C-terminal domain of the SARS-CoV-2 nucleocapsid protein

Nucleocapsid (N) protein plays crucial roles in the life cycle of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), including the formation of ribonucleoprotein (RNP) complex with the viral RNA. Here we reported the crystal structures of the N-terminal domain (NTD) and C-terminal domain...

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Detalles Bibliográficos
Autores principales: Luan, Xiaodong, Li, Xinming, Li, Yufan, Su, Gengchen, Yin, Wanchao, Jiang, Yi, Xu, Ning, Wang, Feng, Cheng, Wang, Jin, Ye, Zhang, Leike, Xu, H. Eric, Xue, Yi, Zhang, Shuyang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science China Press. Published by Elsevier B.V. and Science China Press. 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605790/
https://www.ncbi.nlm.nih.gov/pubmed/36317101
http://dx.doi.org/10.1016/j.scib.2022.10.021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605790/
https://www.ncbi.nlm.nih.gov/pubmed/36317101
http://dx.doi.org/10.1016/j.scib.2022.10.021

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