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Antiviral drug design based on structural insights into the N-terminal domain and C-terminal domain of the SARS-CoV-2 nucleocapsid protein
Nucleocapsid (N) protein plays crucial roles in the life cycle of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), including the formation of ribonucleoprotein (RNP) complex with the viral RNA. Here we reported the crystal structures of the N-terminal domain (NTD) and C-terminal domain...
Autores principales: | Luan, Xiaodong, Li, Xinming, Li, Yufan, Su, Gengchen, Yin, Wanchao, Jiang, Yi, Xu, Ning, Wang, Feng, Cheng, Wang, Jin, Ye, Zhang, Leike, Xu, H. Eric, Xue, Yi, Zhang, Shuyang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Science China Press. Published by Elsevier B.V. and Science China Press.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605790/ https://www.ncbi.nlm.nih.gov/pubmed/36317101 http://dx.doi.org/10.1016/j.scib.2022.10.021 |
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