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Structure of trimeric pre-fusion rabies virus glycoprotein in complex with two protective antibodies
Rabies virus (RABV) causes lethal encephalitis and is responsible for approximately 60,000 deaths per year. As the sole virion-surface protein, the rabies virus glycoprotein (RABV-G) mediates host-cell entry. RABV-G’s pre-fusion trimeric conformation displays epitopes bound by protective neutralizin...
Autores principales: | Ng, Weng M., Fedosyuk, Sofiya, English, Solomon, Augusto, Gilles, Berg, Adam, Thorley, Luke, Haselon, Anna-Sophie, Segireddy, Rameswara R., Bowden, Thomas A., Douglas, Alexander D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9605875/ https://www.ncbi.nlm.nih.gov/pubmed/35985336 http://dx.doi.org/10.1016/j.chom.2022.07.014 |
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